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Description
Invivo Anti-Mouse LPAM-1 (Integrin α4β7) Recombinant mAbProduct Specification Host Rat Antigen LPAM 1 (Integrin 47) Location Cell membrane Accession P26011 Clone Number S 3206 Antibody Type Rat mAb Isotype Rat IgG2a,k Application FCM, in vivo Integrin 47 neutralization Reactivity Ms Purification Protein G Concentration 5 mg ml Purity >95% (Determined by SDS PAGE) Endotoxin <1EU mg Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, containing no preservative Stability & Storage 2
Product Specification
| Host | Rat |
| Antigen | LPAM-1 (Integrin α4β7) |
| Location | Cell membrane |
| Accession | P26011 |
| Clone Number | S-3206 |
| Antibody Type | Rat mAb |
| Isotype | Rat IgG2a,k |
| Application | FCM, in vivo Integrin α4β7 neutralization |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Purity | >95% (Determined by SDS-PAGE) |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 2 to 8 °C for 2 weeks under sterile conditions; |
Background
LPAM-1 (Lymphocyte Peyer’s patch Adhesion Molecule-1), also designated integrin α4β7, is a 150/130 kDa heterodimeric surface glycoprotein of the integrin immunoglobulin superfamily that is constitutively expressed on naive T and B cells, up-regulated on gut-homing memory CD4⁺ T cells and IgA-secreting plasma cells by retinoic acid, and serves as the principal homing receptor mediating rolling and firm adhesion of these leukocytes to mucosal vascular addressin MAdCAM-1 on high endothelial venules of Peyer’s patches and intestinal lamina propria, thereby orchestrating their trans-endothelial migration into gut-associated lymphoid tissues during both steady-state immune surveillance and inflammatory bowel diseases, and can also engage VCAM-1 and fibronectin to support lymphocyte trafficking and retention.
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4.6 ★★★★★
Based on 93 reviews
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Product Reviews
★★★★★ 5
Great quality Soap
Scent: Oatmeal Shea (Unsented)
This natural bar soap is absolutely fantastic! I’ve purchased it multiple times now, and it has never disappointed. The quality is consistent with every bar — it lathers well, cleans thoroughly, and leaves my skin feeling fresh without any dryness.
I really appreciate that it’s made with natural ingredients, and the scent is clean and refreshing without being overpowering. It lasts a good amount of time, making it a great value as well.
Overall, this is a high-quality soap I keep coming back to. The fact that I’ve bought it multiple times says it all — it’s reliable, gentle, and one of the best natural soaps I’ve used. Highly recommended!
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Reviewed in the United States on November 7, 2025
★★★★★ 3
Sometimes Size Does Matter
Scent: Alpine & Spice, Scent: Alpine & Spice
Let me just get this out of the way now the soap itself smells decent, nothing wrong there. I only wish I got another cent. Not that this one smells bad it’s just it wasn’t my cup of tea. I’m mostly disappointed about the size because I’ve been through this before. The soaps themselves are not big enough to fill out the box as you can spot in some of the pictures and video. I honestly feel like the soap size was different in the pictures of the customer reviews that I saw. Each bar may last me a week and a half and that’s with a soap saver. To be honest, the box that it came in would fit two decent size soaps if they filled out the box.
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Reviewed in the United States on November 19, 2025
★★★★★ 5
As expected
Scent: vanilla orange
Love the scents of this soap. It's gentle on my skin and leaves me clean, fresh and soft.
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Reviewed in the United States on May 28, 2026
★★★★★ 5
A Comprehensive Balanced History of the Guadalcanal Campaign -- Must Read!
Format: Hardcover
I've read a number of good books on the Guadalcanal campaign, and always thought that "Neptune's Inferno" by Hornfischer was the absolute best.
I was wrong. Although Hornfischer does a superb account of the Navy and its travails and triumphs, Inferno doesn't delve deeply into the Marine (and Army) land battles. This book does both. Moreover, it provides a continuous timeline of both, and does so in such a way that the reader better understands both as related actions. For instance, I was never really aware that for the first three and a half months the Americans controlled the seas during daylight, and the Japanese at night (sounds a little like Viet Nam). The November 13 sea battle between Americans and Japanese -- in which US cruisers took on Japanese battleships and two American admirals died -- was in fact a clash of a major last ditch effort by the Japanese to reinforce their troops and destroy Henderson Field, which would have allowed them to control the seas both day and night. By that time there had been multiple bloody battles ashore between the Marines and Japanese, with the balance favoring the Marines, but if the Japanese had wrested control of the airfield and seas that would have been old history. The book includes a good view from the Japanese perspective, and some little known historical tidbets as well, e.g., Guadalcanal received its name from the Spanish home town of a ships officer who accompanied Spanish explorer Don Alvaro Medana, who discovered the island during a 1568 expedition to discover the fabled King Solomon's gold mines. Who knew? :-)
Bottom line: I highly recommend this book, both for its balanced coverage of the entire campaign, land and sea, and even more for its integrated narrative -- you know what was taking place (or had taken place) on almost a day-by-day basis, which allows the reader to fully appreciate how actions ashore influenced those at sea, and vice versa.
IMO, a must read, even for those who thought (like me) that they knew it all!
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Reviewed in the United States on October 12, 2017
★★★★★ 5
The Island Of Death
Format: Hardcover
On August 7th, 1942, American Marines stormed ashore on Guadalcanal. What lay before them was a six-month odyssey of fighting against the best of what the Japanese had to offer. In this fine book, author Joseph Wheelan describes the battle that turned the tide in the Pacific War.
The Japanese had started construction of an airfield on Guadalcanal. If completed, Japanese aircraft would be able to harass American convoys and threaten Australia. The Americans seized the airfield and eventually, planes from the Cactus Air Force began attacking the Japanese.
Throughout the book, the reader learns about all phases of the Guadalcanal campaign, including the battles of Alligator Creek and Bloody Ridge. On the sea, the Americans and Japanese slugged it out at Savo Island, as well as the great naval battles of November, 1942. Names such as Chesty Puller, John Baslone, "Archie" Vandegrift, Joe Foss, and "Bull" Halsey became household names in the United States.
Each side lost many men, ships, and planes, but the tenacity and, finally, the industrial might and the ability to rapidly replace losses, led the Americans to victory. Never again would the Japanese regain the offensive in the Pacific War.
"Midnight in the Pacific" is a very good book, and the author has done a good job of describing all of the main points of the battle. Each chapter is broken down into a single month's worth of action, and the narrative is well-written. Highly recommended.
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Reviewed in the United States on September 25, 2017
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